Though we agree with their argument that language is shaped by domain-general learning processes, Christiansen & Chater (C&C) neglect to detail how the development of these processes shapes language change. We discuss a number of examples that show how developmental processes at multiple levels and timescales are critical to understanding the origin of domain-general mechanisms that shape language evolution.

This article describes some potential uses of Bayesian estimation for time-series and panel data models by incorporating information from prior probabilities in addition to observed data. Drawing on econometrics and other literatures we illustrate the use of informative “shrinkage” or “small variance” priors while extending prior work on the general cross-lagged panel model. Using a panel dataset of national income and subjective well-being we describe three key benefits of these priors. First, they shrink parameter estimates toward zero or toward each (...) other for time-varying parameters, which lends additional support for an income → SWB effect that is not supported with maximum likelihood. This is useful because, second, these priors increase model parsimony and the stability of estimates and thus improve out-of-sample predictions and interpretability, which means estimated effect should also be more trustworthy than under ML. Third, these priors allow estimating otherwise under-identified models under ML, allowing higher-order lagged effects and time-varying parameters that are otherwise impossible to estimate using observed data alone. In conclusion we note some of the responsibilities that come with the use of priors which, departing from typical commentaries on their scientific applications, we describe as involving reflection on how best to apply modeling tools to address matters of worldly concern. (shrink)

Precision targeting of specific white matter bundles that traverse the subcallosal cingulate has been linked to efficacy of deep brain stimulation for treatment resistant depression. Methods to confirm optimal target engagement in this heterogenous region are now critical to establish an objective treatment protocol. As yet unexamined are the time-frequency features of the SCC evoked potential, including spectral power and phase-clustering. We examined these spectral features—evoked power and phase clustering—in a sample of TRD patients with implanted SCC stimulators. Electroencephalogram was (...) recorded during wakeful rest. Location of electrical stimulation in the SCC target region was the experimental manipulation. EEG was analyzed at the surface level with an average reference for a cluster of frontal sensors and at a time window identified by prior study. Morlet wavelets generated indices of evoked power and inter-trial phase clustering. Enhanced phase clustering at theta frequency was observed in every subject and was significantly correlated with SCC-EP magnitude, but only during left SCC stimulation. Stimulation to dorsal SCC evinced stronger phase clustering than ventral SCC. There was a weak correlation between phase clustering and white matter density. An increase in evoked delta power was also coincident with SCC-EP, but was less consistent across participants. DBS evoked time-frequency features index mm-scale changes to the location of stimulation in the SCC target region and correlate with structural characteristics implicated in treatment optimization. Results also imply a shared generative mechanism between evoked potentials evinced by electrical stimulation and evoked potentials evinced by auditory/visual stimuli and behavioral tasks. Understanding how current injection impacts downstream cortical activity is essential to building new technologies that adapt treatment parameters to individual differences in neurophysiology. (shrink)

SummaryThis paper attempts to develop an interpretation of Kant's transcendental idealism which is based upon his critique of transcendental realism. It is argued that given Kant's transcendental distinction, all non‐ or pre‐critical philosophies, even Berkeleian phenomenalism are transcendentally realistic. This paradoxical result is used as the basis for an analysis of Kant's resolution of the mathematical antinomies, wherein this resolution is seen both as an “indirect proof” of transcendental idealism and as a refutation of transcendental realism. Finally, it is claimed (...) that Kant's idealism, at least insofar as it is established by means of a refutation of transcendental realism, is methodological rather than metaphysical, viz. it involves a claim about how the sensible world is to be considered in transcendental reflection, not a claim about the “real nature” of this world.RésuméCet article essaye de développer une interprétation de l'idéalisme transcendental de Kant, interprétation basée sur sa critique du réalisme transcendental. L'auteur montre que, si l'on accepte la distinction transcendentale de Kant, toutes les philosophies non critiques et précritiques sont transcendentalement réalistes, y compris le phénoménalisme de Berkeley. A partir de ce résultat paradoxal, il analyse la manière dont Kant résoud les antinomies mathématiques: cette résolution apparaît à la fois comme preuve indirecte de l'idéalisme transcendental et comme une réfutation du réalisme transcendental. L'auteur est finalement d'avis que l'idéalisme de Kant, du moins lorsqu'il est justifié par une réfutation du réalisme transcendental, est plus méthodologique que métaphysique, c'est‐à‐dire qu'il déclare comment le monde sensible doit être considéré dans la réflexion transcendentale et non quelle est la véritable nature de ce monde.ZusammenfassungEs wird versucht, eine Interpretation von Kants transzendentalem Idealismus zu entwickeln, die auf seiner Kritik am transzendentalen Realismus — verstanden als derjenige Standpunkt, der systematisch Erscheinung und Ding an sich verwechselt — beruht. Es wird argumentiert, dass — einmal Kants transzendentale Unterscheidung angenommen — aile früheren, vorkritischen Systeme der Philosophie einschliesslich Berkeleys Phänomenalismus transzendental realistisch sind. Dieses paradoxale Ergebnis wird als Basis für eine Analyse von Kants Auflösung der mathematischen Antinomien verwendet, wobei dièse Auflösung sowohl als ein indirekter Beweis für den transzendentalen Idealismus als auch als eine Widerlegung des transzendentalen Realismus gedeutet wird. Es wird schliesslich nahegelegt, dass Kants Idealismus, sofern wenigstens als er sich auf Widerlegung des transzendentalen Realismus abstützt, mehr ein rnethodologischer als ein metaphysischer Idealismus ist. Er statuiert eher über die Art, wie die Sinneswelt in einer transzendentalen Reflexion betrachtet werden soll, als über die Frage, wie die Welt wirklich beschaffen sei. (shrink)

SummaryThis paper attempts to develop an interpretation of Kant's transcendental idealism which is based upon his critique of transcendental realism . It is argued that given Kant's transcendental distinction, all non‐ or pre‐critical philosophies, even Berkeleian phenomenalism are transcendentally realistic. This paradoxical result is used as the basis for an analysis of Kant's resolution of the mathematical antinomies, wherein this resolution is seen both as an “indirect proof” of transcendental idealism and as a refutation of transcendental realism. Finally, it is (...) claimed that Kant's idealism, at least insofar as it is established by means of a refutation of transcendental realism, is methodological rather than metaphysical, viz. it involves a claim about how the sensible world is to be considered in transcendental reflection, not a claim about the “real nature” of this world.RésuméCet article essaye de développer une interprétation de l'idéalisme transcendental de Kant, interprétation basée sur sa critique du réalisme transcendental . L'auteur montre que, si l'on accepte la distinction transcendentale de Kant, toutes les philosophies non critiques et précritiques sont transcendentalement réalistes, y compris le phénoménalisme de Berkeley. A partir de ce résultat paradoxal, il analyse la manière dont Kant résoud les antinomies mathématiques: cette résolution apparaît à la fois comme preuve indirecte de l'idéalisme transcendental et comme une réfutation du réalisme transcendental. L'auteur est finalement d'avis que l'idéalisme de Kant, du moins lorsqu'il est justifié par une réfutation du réalisme transcendental, est plus méthodologique que métaphysique, c'est‐à‐dire qu'il déclare comment le monde sensible doit être considéré dans la réflexion transcendentale et non quelle est la véritable nature de ce monde.ZusammenfassungEs wird versucht, eine Interpretation von Kants transzendentalem Idealismus zu entwickeln, die auf seiner Kritik am transzendentalen Realismus — verstanden als derjenige Standpunkt, der systematisch Erscheinung und Ding an sich verwechselt — beruht. Es wird argumentiert, dass — einmal Kants transzendentale Unterscheidung angenommen — aile früheren, vorkritischen Systeme der Philosophie einschliesslich Berkeleys Phänomenalismus transzendental realistisch sind. Dieses paradoxale Ergebnis wird als Basis für eine Analyse von Kants Auflösung der mathematischen Antinomien verwendet, wobei dièse Auflösung sowohl als ein indirekter Beweis für den transzendentalen Idealismus als auch als eine Widerlegung des transzendentalen Realismus gedeutet wird. Es wird schliesslich nahegelegt, dass Kants Idealismus, sofern wenigstens als er sich auf Widerlegung des transzendentalen Realismus abstützt, mehr ein rnethodologischer als ein metaphysischer Idealismus ist. Er statuiert eher über die Art, wie die Sinneswelt in einer transzendentalen Reflexion betrachtet werden soll, als über die Frage, wie die Welt wirklich beschaffen sei. (shrink)

Wall, G. Locke's attack on innate knowledge.--Harris, J. Leibniz and Locke on innate ideas.--Greenlee, D. Locke's idea of idea.--Aspelin, G. Idea and perception in Locke's essay.--Greenlee, D. Idea and object in the essay.--Mathews, H. E. Locke, Malebranche and the representative theory.--Alexander, P. Boyle and Locke on primary and secondary qualities.--Ayers, M. R. The ideas of power and substance in Locke's philosophy.--Allison, H. E. Locke's theory of personal identity.--Kretzmann, N. The main thesis of Locke's semantic theory.--Woozley, A. D. Some remarks (...) on Locke's account of knowledge.--Laudan, L. The nature and sources of Locke's views on hypotheses. (shrink)

In spring 2020, COVID-19 and the ensuing social distancing and stay-at-home orders instigated abrupt changes to employment and educational infrastructure, leading to uncertainty, concern, and stress among United States college students. The media consumption patterns of this and other social groups across the globe were affected, with early evidence suggesting viewers were seeking both pandemic-themed media and reassuring, familiar content. A general increase in media consumption, and increased consumption of specific types of content, may have been due to media use (...) for coping strategies. This paper examines the relationship between the stress and anxiety of university students and their strategic use of media for coping during initial social distancing periods in March-April 2020 using data from a cross-sectional survey. We examine links between specific types of media use with psychological well-being concepts, and examine the moderating roles of traits as buffers against negative relationships between stress and anxiety and psychological well-being. Our findings indicate that stress was linked to more hedonic and less eudaimonic media use, as well as more avoidant and escapist media-based coping. Anxiety, on the other hand, was linked to more media use in general, specifically more eudaimonic media use and a full range of media-based coping strategies. In turn, escapist media was linked to negative affect, while reframing media and eudaimonic media were linked to positive affect. Avoidant coping was tied to poorer mental health, and humor coping was tied to better mental health. Hedonic and need-satisfying media use were linked to more flourishing. Hope, optimism, and resilience were all predictive of media use, with the latter two traits moderating responses to stress and anxiety. The findings give a nuanced portrait of college students’ media use during a pandemic-induced shutdown, showing that media use is closely intertwined with well-being in both adaptive and maladaptive patterns. (shrink)

This collection contains the following sixteen essays: "Some Pivotal Issues in Spinoza," by Paul Weiss; "The Deductive Character of Spinoza's Metaphysics," by Michael Hooker; "Spinoza's Ontological Proof," by Willis Doney; "Spinozistic Anomalies," by Jose Benardete; "Some Idealistic Themes in the Ethics," by Robert N. Beck; "Spinoza's Dualism," by Alan Donagan; "Objects, Ideas, and 'Minds': Comments on Spinoza's Theory of Mind," by Margaret D. Wilson; "Parallelism and Complementarity: The Psycho-Physical Problem in the Succession of Niels Bohr," by Hans Jonas; "Spinoza's Political (...) Philosophy: The Lessons and Problems of a Conservative Democrat," by Lewis S. Feuer; "Notes on Spinoza's Critique of Religion," by Hilail Gilden [[sic]] ; "Spinoza and History," by James C. Morrison; "Kant's Critique of Spinoza," by Henry E. Allison; "Hegel's Assessment of Spinoza," by Kenneth L. Schmitz; "Spinoza's Logic of Inquiry: Rationalist or Experientialist?" by Isaac Franck; "De Natura," by Stewart Umphrey; "Analytic and Synthetic Methods in Spinoza's Ethics," by Richard Kennington. (shrink)

BackgroundIn December 2014, China announced that only voluntarily donated organs from citizens would be used for transplantation after January 1, 2015. Many medical professionals worldwide believe that China has stopped using organs from death-row prisoners.DiscussionIn the present article, we briefly review the historical development of organ procurement from death-row prisoners in China and comprehensively analyze the social-political background and the legal basis of the announcement. The announcement was not accompanied by any change in organ sourcing legislations or regulations. As a (...) fact, the use of prisoner organs remains legal in China. Even after January 2015, key Chinese transplant officials have repeatedly stated that death-row prisoners have the same right as regular citizens to “voluntarily donate” organs. This perpetuates an unethical organ procurement system in ongoing violation of international standards.ConclusionsOrgan sourcing from death-row prisoners has not stopped in China. The 2014 announcement refers to the intention to stop the use of organs illegally harvested without the consent of the prisoners. Prisoner organs procured with “consent” are now simply labelled as “voluntarily donations from citizens”. The semantic switch may whitewash sourcing from both death-row prisoners and prisoners of conscience. China can gain credibility only by enacting new legislation prohibiting use of prisoner organs and by making its organ sourcing system open to international inspections. Until international ethical standards are transparently met, sanctions should remain. (shrink)

The Internet and electronic communication technologies have taken the psychological field by storm. From the innovations of new web interventions for easier access to care to the increased ease of client scheduling and communication, these developments have greatly advanced mental health care. However, these advantages are also laced with ethical implications that warrant attention. Without judicious consideration, social media use by psychotherapists can lead to inadvertent self-disclosures to clients that risk damaging the therapeutic alliance, interfering with therapeutic processes, and placing (...) both the client and clinician at risk. A better understanding of the ethical implications of social media use is warranted so that guidelines for appropriate use can be developed and implemented. This article highlights the potential risks associated with social media use by psychotherapists and, in absence of formalized guidelines, offers recommendations for best practices. (shrink)

Two types of interleukin 1 (IL‐1α and IL‐1β) have been defined by purifying the molecules from activated human peripheral blood cells, followed by cloning and expressing the molecules in Escherichia coli. Both types of IL‐1 stimulate proliferation and differentiation of T‐ and B‐lymphocytes and induce cartilage proteoglycan degradation but differ in other properties. For example, demineralization and appears to be a major mediator in the pathogenesis of joint erosion in rheumatoid arthritis. Synthetic adjuvants elicit the production of IL‐1 separate from (...) endogenous pyrogen, and this property is required for the new generation of vaccines based on antigens produced by recombinant DNA technology. (shrink)

It is an observed fact that human populations differ in genetic composition. Some of the inherited diversity is due to combined effects of many genes. Although it would be interesting to know the magnitude and nature of the genetic contribution to some characters under polygenic control, such as intelligence or physique, environmental effects may be so great that no genetic analysis is possible—as Thoday has pointed out earlier in this symposium. With other polygenic characters, such as skin colour, the genetic (...) component is more obvious but still difficult to analyse precisely. The number of genes involved, their frequency and dominance have not been established. This is one of the reasons why selective effects on such characters are not readily measured, although they probably exist. (shrink)

Isaac Deutscher and David King, The Great Purges and C.L.R. James, At the Rendezvous of Victory.

Kurrâ’ya nispet edilen aynı kelimelerdeki edâ farklılıklarının tartışmalara sebep olmasından ötürü kıraat ihtilafı olan kelimelerde ihticâc yapılmasına gereksinim duyulmuştur. Delil getirmek manasında kullanılan ihticâc kavramı, kıraat ihtilafları için söz konusu olduğunda ise kıraat ihtilaflarının sıhhat zemininin ortaya konması kastedilmektedir. Ayrıca 2. asrın sonlarında kıraat tevcîhlerinin yapıldığı müstakil eserler ortaya çıkmakla birlikte kıraat alan yazınına ait genel telifatlarda da kıraat ihticâclarının yapıldığı görülmektedir. Kıraat müelliflerinden biri olan İbnu’l-Cezerî de Neşru’l-ḳırââti’l-‘aşr adlı eserinde zaman zaman kıraat ihticâcına yer vermektedir. Mezkûr eserdeki kıraat ihticâcları (...) hakkında tespit edilebildiği kadarıyla yapılmış tek bir çalışma bulunmaktadır. Fakat bu çalışmada, kıraatten ve bunun dışındaki disiplinlerden yeterince istifade edilmediği belirlenmiştir. Ayrıca selef ulemasının Neşru’l-ḳırââti’l-‘aşr adlı esere ihticâc konusunda etkisi özelinde bir çalışmaya da rastlanmamıştır. Buradan hareketle elinizdeki bu çalışmada, İbnu’l-Ce-zerî’nin kıraat ihticâcına dair uygulamaları Neşru’l-ḳırââti’l-‘aşr adlı eser özelinde incelenmiş, me‘âni’l-Kur’ân ve me‘âni’l-kıraat literatürlerinin ortaya çıktıkları dönem dikkate alınarak h. 2.-4. asırlarda kaleme alınan bu literatürlere ait eserlerin İbnu’l-Cezerî’ye ait kıraat tevcîhlerine etkisinin olup olmadığı araştırılmıştır. Çalışmanın neticesinde İbnu’l-Cezerî’nin yaptığı kıraat tevcîhlerinden ele alınanların bir kısmına, söz konusu üç asırda kaleme alınan me‘âni’l-Kur’ân ve me‘âni’l-kıraat telifatında ekseriyetle yer verilmediği saptanmıştır. İbnu’l-Cezerî’nin ise kıraat ihtilafının olmadığı yerlerde dahi ilgili edâ için ihticâc yaptığı müşahede edilmiştir. Buna ilaveten İbnu’l-Cezerî’nin Neşr’de yaptığı ihticâc uygulamalarının me‘âni’l-Kur’ân ve me‘âni’l-kıraat telifatında yapılan ihticâc işlemleriyle benzeştiği görülmüştür. Yine Neşr’in tevcîh eseri olmaması hasebiyle de İbnu’l-Cezerî tarafından yapılan ihticâcların ihtiyaç merkezli olarak kendini gösterdiği belirlenmiştir. (shrink)

The research presented in this volume demonstrates that it is no longer reasonable to ask whether or not synesthesia is real--we must now ask how we can account ...

This article explores egg freezing experiences of women in Turkey. Since 2014, it has been legal in Turkey to use egg freezing technology for ageing women, while it was previously allowed only for disease-related purposes. In cooperation with a private fertility clinic in Istanbul, the authors conducted 21 interviews with older, single women who held either professional or managerial positions and who were undergoing or had undergone the procedure. Drawing on a qualitative analysis of these interviews, the authors explore the (...) social context in which women postpone motherhood and decide to freeze their eggs. The study also looks at the women’s emotional responses to ageing that were triggered by the experience of egg freezing and their narratives of empowerment as a result of the procedure. (shrink)

Organ donation after brain death has been practiced in China since 2003 in the absence of brain death legislation. Similar to international standards, China’s brain death diagnostic criteria include coma, absence of brainstem reflexes, and the lack of spontaneous respiration. The Chinese criteria require that the lack of spontaneous respiration must be verified with an apnea test by disconnecting the ventilator for 8 min to provoke spontaneous respiration. However, we have found publications in Chinese medical journals, in which the donors (...) were declared to be brain dead, yet without an apnea test. The organ procurement procedures started with initiating “intratracheal intubation for mechanical ventilation after brain death,” indicating that a brain death diagnosis was not performed. The purpose of the intubation was not to resuscitate the patient but rather was directly related to facilitating the explantation of organs. Moreover, it was unmistakably stated in two of these publications that the cardiac arrest was induced in these patients without brain death determination by cold St. Thomas cardioplegic solution or other cold myocardial protection solutions. This means that the condition of these donors neither met the criteria of brain death nor that of cardiac death. In other words, the “donor organs” may well have been procured in these cases from living human beings. Thus, brain death definition is abused in China by some individuals for organ harvesting, and a systematic investigation is needed to clarify the situation of organ donation after brain death in China. (shrink)

Clinical decision making is a challenging task that requires practical wisdom—the practised ability to help patients choose wisely among available diagnostic and treatment options. But practical wisdom is not a concept one typically hears mentioned in medical training and practice. Instead, emphasis is placed on clinical judgement. The author draws from Aristotle and Aquinas to describe the virtue of practical wisdom and compare it with clinical judgement. From this comparison, the author suggests that a more complete understanding of clinical judgement (...) requires its explicit integration with goals of care and ethical values. Although clinicians may be justified in assuming that goals of care and ethical values are implicit in routine decision making, it remains important for training purposes to encourage habits of clinical judgement that are consciously goal-directed and ethically informed. By connecting clinical judgement to patients' goals and values, clinical decisions are more likely to stay focused on the particular interests of individual patients. To cultivate wise clinical judgement among trainees, educational efforts should aim at the integration of clinical judgement, communication with patients about goals of care, and ethical reasoning. But ultimately, training in wise clinical judgement will take years of practice in the company of experienced clinicians who are able to demonstrate practical wisdom by example. By helping trainees develop clinical judgement that incorporates patients' goals of care and ethical reasoning, we may help lessen the risk that ‘clinical judgement’ will merely express ‘the clinician's judgement.’. (shrink)

The exact agreement between the Sommerfeld and Dirac results for the energy levels of the relativistic hydrogen atom (the “Sommerfeld Puzzle”) is analyzed and explained.